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V , 812 2011 . 577.112(063) 28.072 43 ...

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2011

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V

, 812 2011 .

577.112(063) 28.072 43

, 11-04-06042

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( 픻), . - , . - ( ), . ( ) . ISBN 978-5-9274-0475-9 , 2011 . .. .. , 2011 5



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13. N -

H-Trp(Nind-For)-OH ¨

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16. N-

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25.

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(LEMNA MINOR) .., .., .

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DRGA

SYNECHOCYSTIS SP. PCC 6803 ,

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STAPHYLOCOCCUS EPIDERMIDIS

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51.

HETERACTIS CRISPA

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52. N- - MII

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MccE

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HETERACTIS CRISPA

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THERMOCOCCUS SIBIRICUS

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41. Hfq

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43. OmpF YERSINIA PSEUDOTUBERCULOSIS

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THERMOCOCCUS SIBIRICUS

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66.

MYCOBACTERIUM TUBERCULOSIS

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HMGB1

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69.

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71. (6-9) (6-9) Ac-D-SPRG

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74. 70 LPS

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76.

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78.

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79.

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80. PRO-GLY-PRO ACETYL-PRO-GLY-PRO

.., .., .., .........348

81.

70

.., .., .

82. (6-9) Ac-L-MPRG

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83.

2- .., .., .., .., .. 351

84.

.., .., .., .........352

85. -

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86.

COX I COX IV

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87.

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90.

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L1

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92.

CANDIDA RUGOSA

.., .., .., .................361

93.

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.., .., .., ...............362

94.

-

.., .., .., ................363

95. LuDES

450

CYP74B

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96. -

-

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97.

GLi1

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98. -

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31 99. GP39, P23-45 THERMUS

THERMOPHILUS,

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100.

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101. -

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102.

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106.

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109.

.., .., ..

110. - TRIP8b

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32 V

111. HMGB1

.., .., .

112. -

-,

.., .., .., .., .., .., ..

113. GroEL/GroES in vitro: .., .., .., .., .

114. OtTx OXYOPES TAKOBIUS

.., .., .., ...................383

115.

G- CIRL-1

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116.

2

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117.

-

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118. eRF1, -

80S

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119. 35

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120. -

IN VITRO

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121. CHROMATOR Su(Hw)-

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122.

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.., .., .., ..

33 7.

123. L

(PARALITHODES

CAMTSCHATICA)

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124.

.., .., .., .., .., ..

125.

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126.

.., .

127.

-

.., .., .., ............397

128.

- TENEBRIO MOLITOR

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129.

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2+

130. Ca -

MYTILUS EDULIS

.., .., .., ..

131.

.., .., .., .., .., .., .., ............401 132. Cry3Aa BACILLUS THURINGIENSIS

TENEBRIO MOLITOR

.., .., .

133.

.., .., ..

134.

.

34 V

135. BACILLUS PUMILUS 3-19

.., .., .., .................405

136. ,

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.., .., .

137.

IV

TENEBRIO MOLITOR

.., .., .., .., .., .., .

138.

.., .., .., ..............408 8:

139. -

L- RHODOSPIRILLUM RUBRUM

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140. ,

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141.

.., .., .., .., .., .., ..

142.

(44-77)

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143.

FCR1 ,

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148. CHO K1,

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, 142290 , . , 4, .

E-mail: afinkel@vega.protres.ru , , , (, , , , ). (1) , . , . (2) , , . , . , . (3) . ( ) . , (, ) . , . , , .

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. .. , 119121 , . , 10 E-mail: archak@ibmc.msk.ru , 20012003 , . , , , , 1,5% [1]. , .

, 23 2010 , . .

. , (), . , , - , , [2]. .

, 10-24 ( ), 1 . 10-18 [3], 1 L. MRM (Multiple Reaction Monitoring) - BrCN-. , .

1. http://podcasts.aaas.org/science_podcast/SciencePodcast_101217.mp3

2. Saiki, R.K. et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (New York, N.Y.) 239, 487-91(1988).

3. Archakov, A. et al. Biospecific irreversible fishing coupled with atomic force microscopy for detection of extremely low-abundant proteins. Proteomics 9, 1326-43(2009).

41

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. .. .. , 117997 , . -, 16/10 E-mail: luk@ibch.ru Aequorea victoria (Green Fluorescent Protein, GFP) . GFP. , GFP- Anthozoa, Copepoda, ().

, , . , , KillerRed . . , KillerRed .

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. .. , 199034 .-, . , 6 - , 197110 .-, . , 3 E-mail: khavinson@gerontology.ru . , , .

, CD34+ CD14+ (), CD3+ ( -), CD4+ (-) CD8+ ( -). Lys-Glu-Asp CD4+CD8+ -. , , , , , . Xenopus laevis . Ala-Glu-Asp-Gly , Lys-Glu-Asp-Pro , , Lys(-Glu-OH) . , Ala-Glu-Asp-Gly, Lys-GluAsp-Pro Lys(-Glu-OH) Xenopus laevis -, . Ala-Glu-Asp-Gly 6.8 CGRP 2, 9 , . LysGlu-Asp-Trp CXCL12 , .

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45

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47

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:

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