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叛纤酪屠  韧遗型乓  寥了任遗世 - 朽珉梓睇 疱耋瘃
 

怕形宋貌 Materials and methods. 23 amateur boxers, aged 17 - 32, who had repeated mild craniocerebral traumas in the history, were the clinical trial subjects. ...

团滦嗡蚊策

Materials and methods. 23 amateur boxers, aged 17 - 32, who had repeated

mild craniocerebral traumas in the history, were the clinical trial subjects. 30 people

of the similar age were the normal control subjects. They were performed the registration of cognitive evoked potentials (P300), evaluated the latent period of P1,

N1, P2, N2, P3 (P300), N3 (ms) components, the amplitude of P300 complex (mV).

Results. Among the clinical trial subjects the P300 latency duration was above the age norm in 39.13% of cases, while among the normal control subjects it was only 13.33%. Among the clinical trial subjects the P300 amplitude indices were below the age norm in 43.48% of cases, while among the normal control subjects there were only 10%. 9 boxers with repeated mild craniocerebral traumas had cognitive deterioration, the 10 ones had impaired recent memory, and the 6 ones had both cognitive deterioration and impaired recent memory. Having evaluated the evidence of the cognitive impairment in the boxers we observed mild cognitive deterioration in all the cases.

Conclusions. A cognitive evoked potentials method can be used as the early diagnostic and control one for evaluating the corrective measures effectiveness in patients with preclinical cognitive impairment.

Key words: cognitive evoked potentials, craniocerebral trauma, boxer.

鲁漕祛耱 镳 噔蝾鸪:

腆疣怦栝 理漯抽 骂腩滂扈痤忤 .戾.., 漕鲥眚 赅翦漯 礤轲铛仇箴愠 吞老 踌屙 ..伢镨赅. 冷疱襦: 疏库, 怏. .锑獒铕钿, 32.



族犷蜞瘘钼 顺涑 它獬忭 .戾.., 镳铘羼铕, 玎獬潴忄 獬滗畴屙 趔黻龀铐嚯羁 涑嚆眍耱桕 挠 眈蜩蝮 礤轲铛仇箴愠 踌屙 嚓噤屐酬 ..蓄祛溧眍忄.

冷疱襦: 疏库, 怏. .锑獒铕钿, 32, 蝈.: (044) 483-95-35.

杨腩眍忤 坞尻襦礓 彦疸抽钼梓 - 氤赅-礤怵铍钽, 磬箨钼栝 耧斥痤岢蝽桕 獬滗畴屙 趔黻龀铐嚯羁 涑嚆眍耱桕 挠 眈蜩蝮 礤轲铛仇箴愠 踌屙 嚓噤屐酬 ..

蓄祛溧眍忄. 冷疱襦: 疏库, 怏. .锑獒铕钿, 32.

幽 616.8-021 .. 踢宋氯质肋, 2014 .. 腩忤鲫

劳浪惹 仕韧仁-团滦嗡蚊茸叛嗜

汤猛纫臀-信俏屠脱臀-椅涛眯涝茸叛嗜

衔世抢遗伺 廖塑哇 仕韧茸叛嗜 惹嗡刃温劳哇 讶湍形涛 蜗信呐伺腿 腥咽

琶 倚劳言涡汤秩 欣蜒胚屯凵 咽伺形

袜鲨铐嚯 戾滂鲨眈觇 箜桠屦耔蝈 桁. .. 令泐祛朦鲟 骡邃屙桢. 耦怵屐屙眍 礤怵铍钽梃 镳钺脲爨 镳钽眍玎 疣耨眄钽 耜脲痤玎 (醒) 镱耠 镥疴铋 觌桧梓羼觐 囹嚓 怆弪 嚓蝮嚯铋 磬篦眍镳嚓蜩麇耜铋 玎溧麇. 杨忮瘌屙耱忸忄龛 戾蝾漕 疣眄彘 滂嚆眍耱桕 轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策 疣耨眄钽 耜脲痤玎, 桤篦屙桢 觌桧桕-礤轲钼桤筻腓玎鲨铐睇 铖钺屙眍耱彘, 铒疱溴脲龛 痂耜 蝠囗耵铕爨鲨 觌桧梓羼觇 桤铍桊钼囗眍泐 耔礓痤爨 誓醒 镳桠脲赅弪 忭桁囗桢 赅 觌桧桷桉蝾, 蜞 镟鲨屙蝾.

皱朦. 物疱溴腓螯 痂耜 蝠囗耵铕爨鲨 觌桧梓羼觇 桤铍桊钼囗眍泐 耔礓痤爨 誓醒 磬 铖眍忄龛 桤篦屙 觌桧桕-爨沩栩眍-疱珙磬眈眍蝾祛沭圄梓羼觇 镳怆屙栝 镥疴钽 桤钿 溴扈咫桧桤圉梃 潆 箅篦龛 蝾黜铖蜩 滂嚆眍耱桕 镳钽眍玎 玎犷脲忄龛.

锑蝈痂嚯 戾蝾潲. 吾耠邃钼囗 100 犷朦睇 觌桧梓羼觇 桤铍桊钼囗睇 耔礓痤祛. 锐耠邃钼囗 镳钼钿桦囫 磬 爨沩栩眍-疱珙磬眈睇 蝾祛沭圄圊 Siemens, Toshiba 1,5 . 析屙桠嚯 觐腓麇耱忸 汨镥痂眚屙耔忭 铟嚆钼 磬 2 忡忮眄 桤钺疣驽龛. 泥眄 戾蝾滂觇 桉镱朦珙忄腓 潆 铞屙觇 滂磬扈觇 玎犷脲忄龛, 铒疱溴脲龛 祛眍- 桦 祗朦蜩纛赅朦眍耱 镱疣驽龛 镱 觌桧梓羼觇 爨沩栩眍-疱珙磬眈眍-蝾祛沭圄梓羼觇 踵疣牝屦桉蜩赅 鲥朦 铒疱溴脲龛 痂耜 蝠囗耵铕爨鲨 嗜 誓醒.





羊囹桉蜩麇耜簋 钺疣犷蜿 镱塍麇眄 溧眄 镳钼钿桦 桉镱朦珙忄龛屐 镳钽疣祆眍泐 镟赍蜞 Statisti馻 8.0 (凷tatSoft, Inc., 沿) Microsoft瓻xcel 2007 (凪icrosoftCorporation, 沿). 碾 铞屙觇 耱屣屙 觐痧咫鲨铐眍 疋玷 戾驿 铗溴朦睇扈 镱赅玎蝈扈 桉镱朦珙忄 戾蝾 礤镟疣戾蝠梓羼觐 疣磴钼铋 觐痧咫鲨 扬桊戾磬. 署桠簋 玎犷脲忄屐铖蜩 疣耨眄 耜脲痤珙 耩邃 桉耠邃箦禧 镟鲨屙蝾 耱痤桦 镱 嚯泐痂蜢囔 枢镫囗-体殄疣.

绣珞朦蜞螓. 耱囹 镳邃耱噔脲睇 溧眄 3-脲蝽邈 磬犭屙 玎 100 犷朦睇扈 觌桧梓羼觇 桤铍桊钼囗睇 耔礓痤祛 (嗜). 物桉囗 觌桧梓羼觇 爨沩栩眍-疱珙磬眈眍-蝾祛沭圄梓羼觇 铖钺屙眍耱 忄痂囗蝾 嗜. 物疱溴脲睇 觌桧桕-礤轲钼桤筻腓玎鲨铐睇 镱赅玎蝈腓 痂耜 蝠囗耵铕爨鲨 嗜 觌桧梓羼觇 漕耱钼屦睇 疣耨眄 耜脲痤 (誓醒). 需耜 蝠囗耵铕爨鲨 嗜 誓醒 镱恹弪 镳 腩赅腓玎鲨 铟嚆钼 溴扈咫桧桤圉梃 祛珙腓耱铎 蝈脲, 磬腓麒 9 汨镥痂眚屙耔忭 铟嚆钼 2疱骅戾, 镥痂纛赅朦眍泐 铗尻 镱 溧眄 绦. 祟赅腓玎鲨 铟嚆钼 祛珂鬻觐恹 耱痼牝箴圊 漕耱钼屦眍 筲咫梓桠噱 耜铕铖螯 镥疱躅溧 嗜 醒.

孰邂 耠钼: 觌桧梓羼觇 桤铍桊钼囗睇 耔礓痤, 觌桧梓羼觇 漕耱钼屦睇 疣耨眄 耜脲痤, 溴扈咫桧桤圉, 爨沩栩眍-疱珙磬眈磬 蝾祛沭圄.

侣拍磐扰 耦怵屐屙眍 礤怵铍钽梃 镳钺脲爨 疣耨眄钽 耜脲痤玎 恹溴弪 桉觌栩咫铋 嚓蝮嚯铖螯 耦鲨嚯-戾滂鲨眈觐 珥圜桁铖螯, 黩 钺篑腩怆屙 驽耱 蝈麇龛 玎犷脲忄龛 恹耦觐 耱屣屙 痂耜 疣眄彘 耱铋觐 桧忄腓滂玎鲨 镟鲨屙蝾.

湾耢铗 磬 祉钽铟桉脲眄 桉耠邃钼囗 铋 钺豚耱, 觐蝾瘥 疣聒桊桦 磬 镳邃耱噔脲龛 铗眍耔蝈朦眍 镟蝾沐礤玎 玎犷脲忄龛 篑钼屦眈蜮钼嚯 脲麇犴簋 蜞牝桕, 铖蜞弪 祉钽 礤疱眄 忸镳铖钼, 铗眍耔蝈朦眍 牮栩屦桢 疣眄彘 滂嚆眍耱桕 醒.

碾 镱耱囗钼觇 滂嚆眍玎 觌桧梓羼觇 漕耱钼屦睇 疣耨眄 耜脲痤 (誓醒) 礤钺躅滂祛 磬腓麒 铒疱溴脲眄 滂嚆眍耱梓羼觇 牮栩屦桢 [6, 9], 耦汶囫眍 觐蝾瘥 蝈麇龛 玎犷脲忄龛 漕腈眍 磬犭囹 溻 轻. 磬箨. 镳圉 耧斥痤岢. 吞老 242 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策 犷脲 觌桧梓羼觇 囹嚓 玎犷脲忄龛 钺牝桠睇 觌桧梓羼觇 镳桤磬觇 礤 戾礤 溻篚 铟嚆钼 镱疣驽龛. 耠篦噱 铗耋蝰蜮 恹 箨噻囗睇 镳桤磬觐 钺玎蝈朦睇 篑腩忤屐 镱耱囗钼觇 滂嚆眍玎 漕腈眍 猁螯 磬腓麒 绦-牮栩屦桢 滂耨屐桧圉梃 镱疣驽龛 镳铖蝠囗耱忮 忸 怵屐屙 [9].

襄疴 觌桧梓羼觇 镳桤磬觇 玎犷脲忄龛 礤 怦邈溧 耦怙噤帼 疱嚯 怵屐屙屐 邈 磬鬣豚. 犷朦眈蜮 耠篦噱 醒 镥疴 桤钿 溴扈咫桧桤圉梃 镳铗尻噱 忤溴 蜞 磬琨忄屐钽 觌桧梓羼觇 桤铍桊钼囗眍泐 耔礓痤爨 (嗜),觐沅 镳桤磬觐 桉皴扈磬鲨 忸 怵屐屙杌 妁 礤, 镳桤磬觇 桉皴扈磬鲨 镳铖蝠囗耱忮 腓犷 羼螯, 腓犷 铗耋蝰蜮簋 [1].

碾 嗜 赅 镥疴铋 囹嚓 玎犷脲忄龛 踵疣牝屦睇 觌桧梓羼觇 镳桤磬觇 钿眍泐 铟嚆 镱疣驽龛. 袜栳铍邋 桧纛痨囹桠睇 滂嚆眍耱梓羼觇 戾蝾漕, 镱玮铍桁 忤珞嚯桤桊钼囹 忸珈铈睇 铟嚆 溴扈咫桧桤圉梃 鲥眚疣朦眍 礤疴眍 耔耱屐, 怆弪 绦.

泥眄 戾蝾 恹怆弪 祉铈羼蜮屙睇 耋彡腓龛麇耜桢 铟嚆 溴扈咫桧桤圉梃. 项耠邃礤 篁铟礤龛 牮栩屦桢 锑 念磬朦溧 2010 泐潴 镱玮铍弪 篑蜞磬怆桠囹 滂嚆眍 誓醒 赅 祛骓 疣睃 [9].孰桧梓羼赅 爨龛翦耱圉 玎犷脲忄龛 忤溴 祛眍纛赅朦眍泐 镳怆屙 蝠遽箦 忭桁囹咫钽 蝙囹咫钽 磬犭屙 玎 犷朦睇 鲥朦 赅 祛骓 犷脲 疣眄邈 篑蜞眍怆屙 滂嚆眍玎, 铒疱溴脲龛 蜞牝桕 脲麇龛.

绣珞朦蜞螓 礤觐蝾瘥 腩磴栩箐桧嚯 觌桧梓羼觇 桉耠邃钼囗栝 箨噻帼 磬 蝾, 黩 50% 膻溴 镥疱礤聒桴 嗜 蝈麇龛 蜩 脲 疣玮桠噱蝰 疣耨眄 耜脲痤 [8-11]. 项铎 耦忮瘌屙耱忸忄龛 戾蝾漕 疣眄彘 滂嚆眍耱桕 玎犷脲忄龛, 桤篦屙桢 觌桧桕-滂嚆眍耱梓羼觇 铖钺屙眍耱彘, 玎觐眍戾痦铖蝈 蝠囗耵铕爨鲨 嗜 誓醒 怆弪 嚓蝮嚯铋 磬篦眍-镳嚓蜩麇耜铋 玎溧麇.

皱朦 桉耠邃钼囗. 物疱溴脲腓螯 痂耜 蝠囗耵铕爨鲨 觌桧梓羼觇 桤铍桊钼囗眍泐 耔礓痤爨 誓醒 磬 铖眍忄龛 桤篦屙 觌桧桕-爨沩栩眍疱珙磬眈眍-蝾祛沭圄梓羼觇 镳怆屙栝 镥疴钽 桤钿 溴扈咫桧桤圉梃潆 箅篦龛 蝾黜铖蜩 滂嚆眍耱桕 镳钽眍玎 玎犷脲忄龛.

汤遗腥浪 膛椅嫩

橡钼邃屙 觌桧桕-礤怵铍钽梓羼觐, 爨沩栩眍-疱珙磬眈眍-蝾祛沭圄梓羼觐 钺耠邃钼囗桢 100 犷朦睇 嗜 (34 祗骥桧 66 驽睐桧) 忸琊囫蝈 铗 15 漕 50 脲, 耩邃龛 忸琊囫 觐蝾瘥 耦耱噔 28,89 7,22 泐溧.

令朦睇 磬躅滂腓顸 磬 脲麇龛 疏邂耜铎 泐痤漶觐 鲥眚疱 疣耨眄钽 耜脲痤玎 磬 徉珏 泐痤漶觐 觌桧梓羼觐 犷朦龛鳆 4 泐痤溧 疏邂. 袜 镳铗驽龛 怦邈 镥痂钿 磬犭屙 镟鲨屙蜞 疱泱痦, 镥痂钿梓眍耱 疣 34 戾鲟 镳钼钿璎腩顸 耱囗溧痱桤桊钼囗眍 礤怵铍钽梓羼觐 钺耠邃钼囗桢 铞屙赅 趔黻鲨铐嚯 耔耱屐 镱 疣聒桊屙眍 嚯 桧忄 腓滂玎鲨 EDSS [5]. 朽 镱脬钿 镳钼钿桦铖 绦 泐腩忭钽 祛玢.

耠篦, 觐沅 犷朦睇 铗戾鬣腓顸 觌桧梓羼觇 镳怆屙 镱疣驽龛 耧桧眍泐 祛玢, 镳钼钿桦铖 绦 泐腩忭钽 耧桧眍泐 祛玢. 锐耠邃钼囗 镳钼钿桦囫 磬 囡镟疣蜞 Siemens, Toshiba 1,5 . 析屙桠嚯 觐腓麇耱忸 汨镥痂眚屙耔忭 铟嚆钼 磬 2 忡忮眄 桤钺疣驽龛. 泥眄 戾蝾滂觇

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策

桉镱朦珙忄腓 潆 铞屙觇 滂磬扈觇 玎犷脲忄龛, 铒疱溴脲龛 祛眍- 桦 祗朦蜩纛赅朦眍耱 镱疣驽龛 镱 觌桧梓羼觇 爨沩栩眍-疱珙磬眈眍蝾祛沭圄梓羼觇 踵疣牝屦桉蜩赅 鲥朦 铒疱溴脲龛 痂耜 耜铕铖蜩 镥疱躅溧 嗜 誓醒.

羊囹桉蜩麇耜簋 钺疣犷蜿 镱塍麇眄 溧眄 镳钼钿桦 桉镱朦珙忄龛屐 镳钽疣祆眍泐 镟赍蜞 Statisti馻 8.0 (凷tatSoft, Inc., 沿) Microsoft Excel 2007 (凪icrosoft Corporation, 沿).

碾 戾驺痼镲钼 耩噔礤龛 桉镱朦珙忄腓:

) 镳 磬腓麒 疣耧疱溴脲龛, 礤 铗腓黜钽 铗 眍痨嚯钽, 潆 耩噔礤龛 礤 犷脲 溻篚 沭箫:

- -蝈耱 (羊溴眚) 箨噻囗桢 耱屣屙彘 疋钺钿;

) 镳 疣耧疱溴脲龛, 铗腓黜铎 铗 眍痨嚯钽, /桦 囗嚯桤 赅麇耱忮眄 镳桤磬觐: 礤镟疣戾蝠梓羼觇 牮栩屦栝 2 翔瘃铐 潆 耩噔礤龛 滂耧屦耔 蜞犭桷圊 耦镳驽眄铖蜩 22 镳 珥圜屙梃 赅驿铋 觌弪赍 铈桎噱禧 麒皴 礤 戾礤 5;溻篑蝾痤眄栝 蝾黜 牮栩屦栝 澡疣 潆 耩噔礤龛 滂耧屦耔 蜞犭桷圊 耦镳驽眄铖蜩 22 镳 珥圜屙梃 铈桎噱祛泐 麒耠 戾礤 5 镱 牮嚅礤 戾疱 钿眍 觌弪赍, 蜞赕 镳 囗嚯桤 蜞犭桷 耦镳驽龛 2鮊.

碾 铞屙觇 耱屣屙 觐痧咫鲨铐眍 疋玷 戾驿 铗溴朦睇扈 镱赅玎蝈扈 桉镱朦珙忄 戾蝾 礤镟疣戾蝠梓羼觐 疣磴钼铋 觐痧咫鲨 扬桊戾磬.

署桠簋 玎犷脲忄屐铖蜩 疣耨眄 耜脲痤珙 耩邃 桉耠邃箦禧 镟鲨屙蝾 耱痤桦 镱 嚯泐痂蜢囔 枢镫囗-体殄疣.

信怯塑依役 日 瘟延颇磐扰

犷朦睇 嗜 铗戾鬣腓顸 钺牝桠睇 觌桧梓羼觇 镳桤磬觇 钿眍泐 铟嚆 镱疣驽龛. 项 溧眄 蝠艴脲蝽邈 桉耠邃钼囗 磬犭嚯桉 耠邃簋 觌桧梓羼觇 忄痂囗螓 嗜: 25 犷朦睇 (25%) 疱蝠钺箅囵睇 礤怵栩, 21 犷朦眍泐 扈咫栩 (21%), 54 (54%) 耱忸腩恹 磬痼龛.

襄疴梓睇 觌桧梓羼觇 镳怆屙 犷脲珥 鬣 磬犭嚯桉 忤溴 耱忸腩恹 磬痼龛: 汶噻钿忤汔蝈朦睇 磬痼龛, 忮耱栳箅痦 磬痼龛, 镥痂翦痂麇耜栝 镟疱 扈扈麇耜桴 禧, 礤怵嚯汨 蝠铋龛黜钽 礤疴.

蝈麇龛 怦邈 镥痂钿 磬犭屙 52 犷朦睇 嗜 疣玮桦 誓醒. 佯邃 桴 犷朦睇 猁 镳钼邃屙 囗嚯桤 蝠囗耵铕爨鲨 嗜 誓醒 躅溴 磬犭屙: 玎 镥痂钿 6 戾鲥, 12 戾鲥, 18 戾鲥 24 戾鲟. 蝈麇龛 6 戾鲥 47,5% 镟鲨屙蝾 嗜 疣玮桦 醒, 12 戾鲥 87,5% 镟鲨屙蝾, 24 戾鲟 100% 犷朦睇 嗜 蝠囗耵铕扈痤忄腭 醒. 镱耠邃簋 12 戾鲥 桉耠邃钼囗 (3 泐 磬犭屙) 禧 礤 铗戾鬣腓 耠篦噱 蝠囗耵铕爨鲨 玎犷脲忄龛. 吾 镳钽眍 牦祗蜩忭 鬣耱铗 疱鲨滂忸 玎犷脲忄龛 镟鲨屙蝾 滂嚆眍珙 嗜 镳 邈 蝠囗耵铕爨鲨 誓醒 镳邃耱噔脲 痂.1, 沅 恹怆弪 镱耱屣屙眍 筲咫梓屙桢 漕腓 犷朦睇 箐腓礤龛屐 耩铌 磬犭屙.

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 244 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策 需. 1. 鼠祗蜩忭 鬣耱铗 玎犷脲忄屐铖蜩 犷朦睇 嗜 亦觇 钺疣珙, 襦祛 恹耦觐 鬣耱铗 蝠囗耵铕爨鲨 嗜 誓醒 猁豚 镥疴 泐 镱耠 疣玮栩 嗜.

悟眍耔蝈朦眍 鬣耱铗 疣玮栩 誓醒 犷朦睇 疣珉梓睇扈 觌桧梓羼觇扈 忄痂囗蜞扈 嗜, 镱塍麇睇 耠邃簋 溧眄. 佯邃 犷朦睇 疱蝠钺箅囵睇 礤怵栩铎 10 桤 25 (40%) 疣玮桦 誓醒. 需耜 疣玮栩 誓醒 潆 犷朦睇 扈咫栩铎 猁 恹: 11 桤 21觌桧梓羼觇 耠篦噱 (52.4%) 蝈麇龛 3 脲 疣玮桦 誓醒. 袜栳铍桁 痂耜 疣玮栩 誓醒 猁 犷朦睇 耦 耱忸腩恹扈 磬痼龛扈 57.4% ( 31 犷朦眍泐 桤 54).

令朦睇 疣珥 觌桧梓羼觇扈 忄痂囗蜞扈 嗜 猁腩 镳钼邃屙 溴蜞朦眍 觌桧桕-礤怵铍钽梓羼觐 桉耠邃钼囗桢, 躅溴 觐蝠钽 猁腓 恹怆屙 铖钺屙眍耱 礤怵铍钽梓羼觐泐 耱囹篑 (蜞.1).

犷朦睇 嗜 忤溴 耱忸腩恹 磬痼龛 磬犭嚯桉 汶噻钿忤汔蝈朦睇 觐铕滂磬蝾痦 磬痼龛. 拟桡囹咫 疣耨蝠铋耱忄 铗戾鬣腓顸 犷朦睇 扈咫栩铎 忤溴 龛骓邈 镟疣镟疱玎 蝈蝠囡囵彗, 蜞赕 黧怦蜮栩咫 镱 镳钼钿龛觐忸祗 蜩矬.

佯邃 犷朦睇 嗜, 觐蝾瘥 镳铞羼皴 磬泐 磬犭屙 疣玮桦 誓醒, 镳孱犭噤嚯 溻桡囹咫 觐铕滂磬蝾痦 磬痼龛.

佯邃 漯筱桴 磬痼龛 犷朦睇 嗜 镳 蝠囗耵铕爨鲨 醒 磬犭嚯桉 蜞赕 磬痼龛 赅 镱忮瘐眍耱眍 蜞 汶筢铌铋 黧怦蜮栩咫铖蜩, 蝾 麒耠 耥桄屙桢 忤狃圉桀眄铋.

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策

   

项 溧眄 绦 桉耠邃钼囗 犷朦睇 嗜 禧 铒疱溴腓腓 鬣耱铗 镱疣驽龛 溴扈咫桧桤桊簋 镳铞羼耦 篦囫蜿钼 泐腩忭钽 祛玢 /桦 耧桧眍泐 祛玢. 橡钼钿桦 篦弪 铟嚆钼 溴扈咫桧桤圉梃 汨镥痂眚屙耔忭 2-疱骅戾.

13 犷朦睇 磬犭嚯铖 祛眍纛赅朦眍 镱疣驽龛 磬腓麒屐 1 铟嚆 钿眍 桤 篦囫蜿钼 祛玢, 87- 祗朦蜩纛赅朦眍 磬腓麒屐 铟嚆钼 礤耜铍桴 蝾镱沭圄梓羼觇 珙磬 耦汶囫眍 觌囫耔翳赅鲨 Miller D. (2004) [7].

祟赅腓玎鲨 鬣耱铗 镱疣驽龛 篦囫蜿钼 泐腩忭钽 祛玢 耧桧眍泐 祛玢 镳邃耱噔脲睇 磬 痂.2.

需. 2. 暑腓麇耱忸 铟嚆钼 溴扈咫桧桤圉梃 犷朦睇 嗜 疣珥 珙磬 锐躅 桤 溧眄 痂. 3, 犷朦睇 嗜 鬣 怦蝠鬻嚯囫 镥痂忮眚痂牦痦 腩赅腓玎鲨 铟嚆钼 溴扈咫桧桤圉梃 (63%), 祛珙腓耱铄 蝈腩 (28%), 腩犴 蝈戾眄 漕腓 镱塍痂 (26 % 24% 耦铗忮蝰蜮屙眍), 耋彡铕蜩赅朦睇 铗溴臌 (23%) 轫 铗溴 耧桧眍泐 祛玢 (23%), 疱驽 镱疣驵腓顸 琊栩咫 狍沭, 犭邃睇 瘥, 忭篁疱眄 赅锺箅, 塍麒耱 忮礤, 蹊噻爨 觐疣 镳弼屙蝠嚯铋 桤忤腓睇.

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策

犷朦睇 嗜 镳 绦-桉耠邃钼囗梃 恹怆腓 祗朦蜩纛赅朦眍 镱疣驽龛 溴扈咫桧桤桊簋 镳铞羼耦 疣珥 篦囫蜿钼 泐腩忭钽 祛玢 [7]. 奏 恹怆腓 耦麇蜞眄铄 镱疣驽龛 耠邃簋 珙 腩赅腓玎鲨 铟嚆钼 溴扈咫桧桤圉梃: 镥痂忮眚痂牦痦 钺豚耱 祛珙腓耱铄 蝈腩 镱疣驵腓顸 20%, 腩犴 蝈戾眄 漕腓 17%, 镥痂忮眚痂牦痦 钺豚耱 蝈戾眄 漕腓 16%, 耋彡铕蜩赅朦磬 镥痂忮眚痂牦痦 钺豚耱 15%, 耋彡铕蜩赅朦磬 钺豚耱 祛珙腓耱铄 蝈腩 12%, 祛珙腓耱铄 蝈腩 祛耱 12%, 镥痂忮眚痂牦痦 钺豚耱, 腩犴 蝈戾眄 漕腓 11%. 奏耱铗 耦麇蜞眄钽 镱疣驽龛 漯筱桴 珙 祛玢 猁豚 戾睃 10%.蔓怆屙 镳爨 耩邃 觐痧咫鲨铐磬 疋琰 戾驿 腩赅腓玎鲨彘 铟嚆钼 蝈戾眄 腩犴 漕, 蝈戾眄 忤耦黜 漕, 祛珙腓耱铎 蝈脲 祛耱. 项塍麇眄 疱珞朦蜞螓 耱囹桉蜩麇耜 漕耱钼屦睇 (r=0,50, 0,05).

袜扈 猁豚 铞屙屙 痂耜 耜铕铖螯 疣玮栩 誓醒 犷朦睇 嗜 玎忤耔祛耱 铗 腩赅腓玎鲨 铟嚆钼溴扈咫桧桤圉梃 磬 2-忡忮眄 桤钺疣驽龛, 桴 觐腓麇耱忄 磬腓麒 镥痂纛赅朦眍泐铗尻.需耜 疣玮栩 誓醒 蝈 桦 桧 镟鲨屙蝾 嗜 猁 铞屙屙 镱 磬腓麒 桦 铗耋蝰蜮棹 铟嚆钼 溴扈咫桧桤圉梃 铒疱溴脲眄 篦囫蜿圊 泐腩忭钽 耧桧眍泐 祛玢 (蜞犭. 2.) 亦犭桷 2 需耜 蝠囗耵铕爨鲨 嗜 醒 玎忤耔祛耱 铗 腩赅腓玎鲨 铟嚆钼 溴扈咫桧桤圉梃

   

枢 忤漤 桤 蜞犭. 2, 磬腓麒 铟嚆钼 祛珙腓耱铎 蝈脲 漕耱钼屦眍 筲咫梓桠嚯 痂耜 疣玮栩 醒 犷朦睇 嗜. 袜腓麒 铟嚆钼 镥痂忮眚痂牦痦铋 钺豚耱 怆弪 犷脲 犭嚆铒痂蝽 羿牝铕铎 潆 镳钽眍玎 蝠囗耵铕爨鲨 嗜 醒 溧眄铋 赅蝈泐痂 镟鲨屙蝾, 蜞 赅 疣玮栩桢 玎犷脲忄龛 忸珈铈眍 麇疱 犷脲 潆栩咫 镥痂钿 磬犭屙.

帖 耩噔龛腓 耜铕铖螯 蝠囗耵铕爨鲨 嗜 醒 镳 疣珉梓眍 腩赅腓玎鲨 铟嚆钼 溴扈咫桧桤圉梃 泐腩忭铎 耧桧眍 祛玢. 橡 腩赅腓玎鲨 铟嚆钼 祛珂鬻觐恹 耱痼牝箴圊 嗜 蝠囗耵铕扈痤忄腭 醒 猁耱疱, 麇 镳 邈 铗耋蝰蜮梃. 橡 磬腓麒 铟嚆钼 铗 桧蝈疴嚯 怵屐屙 耦耱噔 8,04 3,75 戾鲥, 镳 铗耋蝰蜮梃 11,23 7,04 戾鲟 (痂. 3).

需. 3.殃铕铖螯 蝠囗耵铕爨鲨 嗜 醒 镳 腩赅腓玎鲨 铟嚆钼 祛珂鬻觐恹 耱痼牝箴圊.

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策 暑腓麇耱忸 铟嚆钼 溴扈咫桧桤圉梃 镳 嗜 祛驽 桁弪 镳钽眍耱梓羼觐 珥圜屙桢 潆 疣玮栩 誓醒. 疣犷蝈 Nielsen J.M. et al. [8] 猁腩 铗戾麇眍, 黩 觐腓麇耱忸 铟嚆钼 溴扈咫桧桤圉梃 9 磬 2-忡忮眄 桤钺疣驽龛 怆弪 镳钽眍耱梓羼觇 礤犭嚆铒痂蝽 羿牝铕铎 潆 镟鲨屙蝾 嗜.

相鲨屙螓 猁腓 疣耧疱溴脲睇 磬 2 沭箫稃 镱 觐腓麇耱怏 铟嚆钼 溴扈咫桧桤圉梃 镱 溧眄 绦:

1) 觐腓麇耱忸 铟嚆钼 9 (37 犷朦睇);

2) 觐腓麇耱忸 铟嚆钼 9 (63 犷朦睇);

如 63 犷朦睇 嗜 觐腓麇耱忸 铟嚆钼 9 36 镱耠邃簋 疣玮桦 誓醒 ( 57,1%). 如 37 犷朦睇 嗜 觐腓麇耱忸 铟嚆钼 9 16 玎 怵屐 磬犭屙 疣玮桦 誓醒 ( 43,2% ). 犷朦睇 觐腓麇耱忸 铟嚆钼 9 猁 犷朦 痂耜 疣玮栩 疣耨眄钽 耜脲痤玎, 麇 犷朦睇 9 铟嚆钼 溴扈咫桧桤圉梃 镱 溧眄 绦 (0,05).

橡 铞屙赍 怆龛 觐腓麇耱忄 铟嚆钼 磬 绦 犷朦睇 嗜 磬 耜铕铖螯 邈 镥疱躅溧 誓醒, 禧 铞屙桦 牦祗蜩忭簋 鬣耱铗 蝠囗耵铕爨鲨 嗜 醒 镱 觐腓麇耱怏 铟嚆钼 磬 绦 (痂. 4).

需. 4. 鼠祗蜩忭 鬣耱铗 蝠囗耵铕爨鲨 嗜 醒 镱 觐腓麇耱怏 铟嚆钼 磬 绦 帖 铞屙桦 怆龛 绦-镳桤磬赅 镥痂纛赅朦眍泐 铗尻, 蜞 磬琨忄屐钽 塍麇忸泐 耔礓痤爨 耱痤 忸耧嚯栩咫铋 溴扈咫桧桤圉梃 磬 痂耜 耜铕铖螯 蝠囗耵铕爨鲨 嗜 誓醒.

项 磬 溧眄 磬腓麒 镥痂纛赅朦眍泐 铗尻 磬 绦 犷朦睇 嗜 筲咫梓桠嚯 痂耜 邈 蝠囗耵铕爨鲨 醒. 枢 忤漤 桤 蜞.3 耩邃 犷朦睇 嗜 23 麇腩忮 恹怆腭 镥痂纛赅朦睇 铗尻 磬 绦, 桤 觐蝾瘥 17 犷朦睇 (73,9%) 蝈麇龛 3- 脲 疣玮桦 誓醒. 佯邃 犷朦睇 轻. 磬箨. 镳圉 耧斥痤岢. 吞老 250 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策 嗜 徨 磬腓麒 镥痂纛赅朦眍泐 铗尻 磬 绦, 钺 觐腓麇耱忸 觐蝾瘥 耦耱噔腩 77 麇腩忮, 35 磬 镳铗驽龛 磬泐 桉耠邃钼囗 磬犭嚯囫 蝠囗耵铕爨鲨 醒, 黩 耦耱噔桦 45,4%. 碾 溧眄钽 镱赅玎蝈 2=4,66, =0,03 ( 镱镳噔觐 慑轵襦), 黩 耦铗忮蝰蜮箦 漕耱钼屦眍祗 铗腓麒.

亦犭桷 3 码龛 镥痂纛赅朦眍泐 铗尻 磬 蝠囗耵铕爨鲨 醒 佯邃礤 怵屐 镥疱躅溧 醒 耦耱噔腩 10,116,57 戾鲥 镳 磬腓麒 镥痂纛赅朦眍泐 铗尻, 蝾 怵屐 赅 镳 铗耋蝰蜮梃 邈 9,45,4 戾鲟. 碾 镱塍麇眄 溧眄 t=-0,41; df=50 p=0,68, 蝾 羼螯 磬腓麒 桦 铗耋蝰蜮桢 镥痂纛赅朦眍泐 铗尻 礤 桁咫 漕耱钼屦眍泐 怆龛 磬 桧蝈疴嚯 怵屐屙 潆 蝠囗耵铕爨鲨 嗜 醒.

论挛嫩

1. 暑祜脲犟眍 觌桧桕-礤怵铍钽梓羼觐, 礤轲钼桤筻腓玎鲨铐眍 钺耠邃钼囗桢 镱赅玎腩, 黩 铖眍忭 觌桧梓羼觇扈 忄痂囗蜞扈 嗜 怆 疱蝠钺箅囵睇 礤怵栩 (25% 犷朦睇), 镱镥疱黜 扈咫栩 (21%), 耱忸腩恹 磬痼龛 (54%).

2. 茵艴脲蝽邋 磬犭屙桢 玎 犷朦睇扈 嗜 镱赅玎腩, 黩 礤耢铗 磬 祛眍纛赅朦眍 镳怆屙桢 镥疴铐圜嚯 耔祜蝾祛 玎犷脲忄龛, 龛 桁妣蝰 镳桤磬觇 赅 桤铍桊钼囗眍泐 (13% 耠篦噱) 蜞 祉铈羼蜮屙眍泐 镱疣驽龛 礤疴眍 耔耱屐 (87%), 黩 镱潋忮疰溧腩顸 溧眄 绦.

3. 需耜 蝠囗耵铕爨鲨 嗜 誓醒 镱恹弪 镳 腩赅腓玎鲨 铟嚆钼 溴扈咫桧桤圉梃 祛珙腓耱铎 蝈脲, 磬腓麒 9 汨镥痂眚屙耔忭 铟嚆钼 2-疱骅戾, 镥痂纛赅朦眍泐 铗尻 镱 溧眄 绦. 祟赅腓玎鲨 铟嚆钼 祛珂鬻觐恹 耱痼牝箴圊 漕耱钼屦眍 筲咫梓桠噱 耜铕铖螯 镥疱躅溧 嗜 醒.

髓蝈疣蝮疣

1. 腻扈磬 .. 义疣镨 徨蜞-桧蝽痿屦铐铎 镱耠 镥疴钽 觌桧梓羼觐泐 桤钿 溴扈咫桧桤圉梃 / 腻扈磬 .., 锗鬣眍忄 .., 泥恹漕怦赅 .. // 企痦. 礤怵. 锺桴. 桁. ..暑瘃嚓钼 2006. .78, 6. .5-14.

2. 青踵痤 .. 孰桧桕-桧耱痼戾眚嚯 觐痧咫螓 觌桧梓羼觇 桤铍桊钼囗眍泐 耔礓痤爨 / 青踵痤 .., 念脬桴 .., 念脬桴 .. // 体滂鲨眈觇 嚯囗圊 2011. .14, 1. .114-116.

3. 青踵痤 .. 孰桧桕, 滂嚆眍耱桕, 蝈麇龛 觌桧梓羼觇 桤铍桊钼囗眍泐 耔礓痤爨: 噔蝾疱. 滂. 赅礓. 戾. 磬箨 / 青踵痤 .. - 燕疣蝾, 2011. 22 .

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策

4. Anti-myelin antibodies in clinically isolated syndrome indicate the risk of multiple sclerosis in a Swiss cohort / Greeve I., Sellner J., Lauterburg T. [et al.] // ActaNeurologicaScandinavica. 2007. V. 116. P. 207210.

5. Kurtzke J.F: Rating neurologic impairment in multiple sclerosis:an expanded disability status scale (EDSS) / Kurtzke J.F: // Neurology. -1983. -Vol. 33, N 11. P. 1444-1452.

6. Prediction of conversion from clinically isolated syndrome to clinically definite multiple sclerosis according to baseline MRI findings: comparison of revised McDonald criteria and Swanton modified criteria / Lo C.P., Kao H.W., Chen S.Y.

[et al.] // J. Neurol. Neurosurg. Psychiatry. 2009. Vol. 80. P. 11071109.

7. Role of magnetic resonance imaging with diagnostic criteria for multiple sclerosis / Miller D.H., Filippi M, Fazekas F. [et al.] //Ann. Neurol. - 2004. -Vol. 56. - P. 273.

8. Classification of patients with a clinically isolated syndrome based on signs and symptoms is supported by magnetic resonance imaging results / Nielsen J.M., Moraal B., Polman C.H. [et al.] // Mult. Scler. 2007. Vol. 13, N 6. P. 717-721.

9. Polman C.H. Diagnostic Criteria for Multiple Sclerosis: 2010 Revisions to the McDonald Criteria / Polman C.H., Reingold S.C., Banwell B. // Ann. Neurol. 2011. - Vol. 69. - P.292 302.

10. Modification of MRI criteria for multiple sclerosis in patients with clinically isolated syndromes / Swanton J.K., Fernando K., Dalton C.M. [et al.] // J Neurol.

Neurosurg Psychiatry. 2006. Vol. 77. P. 830833.

11. The Optic Neuritis Study Group. Multiple sclerosis risk after optic neuritis:

Final Optic Neuritis Treatment Trial follow-up // Arch. Neurol. 2008. Vol. 65. P. 727732.

12. Accuracy of CSF and MRI criteria for dissemination in space in the diagnosis of multiple sclerosis / Villar M.L., Garca-Barragn N., Sdaba M.C. [et al.] // J. Neurol. Sci. 2008. Vol. 1. P. 3437.

.. 腩忤鳇赅 理嚯崇 觌稠酬-礤怵铍钽橱龛 蜞 爨沩瞅眍-疱珙磬眈眍蝾祛沭圄橱龛 镱赅珥桕斥 踱铕桴 磬 觌稠橱眍 崇铍忄龛 耔礓痤 忤珥圜屙 痂玷牦 轭泐 蝠囗耵铕爨龀 痤珩龛 耜脲痤 袜龀铐嚯栝 戾滂黜栝 箜斥屦耔蝈 踌. ..令泐祛朦 埋蝮. 耋鬣耥抽 礤怵铍钽晨 镳钺脲爨 镳钽眍珞 痤珩眍泐 耜脲痤珞 锍耠 镥瘌羁 觌稠橱眍 囹嚓 嚓蝮嚯铪 磬箨钼-镳嚓蜩黜桁 玎怃囗.

愉铖觐磬脲眄 戾蝾涑 疣眄 涑嚆眍耱桕 痤珩眍泐 耜脲痤珞, 忤怊屙 觌稠酬-礤轲钼崇嚯崇圉抽龛 铖钺腓忸耱彘, 忤珥圜屙 痂玷牦 蝠囗耵铕爨龀 觌稠橱眍 崇铍忄眍泐 耔礓痤祗 誓醒 镳桠屦蜞 筲嚆, 觌稠出桉虺, 蜞 镟龀喉虺.

体蜞. 妈珥圜栩 痂玷 蝠囗耵铕爨龀 觌稠橱眍 崇铍忄眍泐 耔礓痤祗 誓醒 磬 铖眍獬 忤怊屙 觌稠酬-爨沩瞅眍-疱珙磬眈眍-蝾祛沭圄橱龛 镳獬 镥瘌钽 屣崇钿 溴斐弘稠崇圉晨 潆 镱氤秫屙 蝾黜铖虺 涑嚆眍耱桕 蜞 镳钽眍珞 玎踱铕囗.

轻. 磬箨. 镳圉 耧斥痤岢. 吞老 252 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策 锑蝈鸪嚯 戾蝾滂. 吾耱彐屙 100 踱铕桴 觌稠橱眍崇铍忄龛 耔礓痤祛. 念耠充驽眄 镳钼钿桦铖 磬 爨沩瞅眍-疱珙磬眈龛 蝾祛沭圄圊 Siemens, Toshiba 1,5 . 析稠嚯 瓿朦瓿耱 愠镥鸪眚屙耔忭桴 忸沩棂 磬 2 玮噫屙桴 珙狃噫屙. 殖 戾蝾滂觇 忤觐痂耱嚯 潆 铞稠觇 滂磬斐觇 玎踱铕囗, 忤珥圜屙 祛眍- 噌 祗朦蜩纛赅朦眍耱 镱疣珀 镱 觌稠橱龛 爨沩瞅眍-疱珙磬眈眍-蝾祛沭圄橱龛 踵疣牝屦桉蜩赅 戾蝾 忤珥圜屙 痂玷牦 蝠囗耵铕爨龀 什 誓醒. 羊囹桉蜩黜 钺痤彡 铗痂爨龛 溧龛 镳钼钿桦 忤觐痂耱囗 镳钽疣祉钽 镟赍蝮 Statisti馻 8.0 ("StatSoft, Inc"., 沿) Microsoft Excel 2007 ("Microsoft Corporation", 沿). 碾 铞稠觇 斐痂 觐疱龀轫钽 玮'珀 斐 铌疱扈扈 镱赅珥桕囔 忤觐痂耱囗栝 戾蝾 礤镟疣戾蝠梓眍 疣磴钼羁 觐疱龀 扬桊戾磬. 署桠 玎踱铕囗铖虺 痤珩龛 耜脲痤珙 皴疱 漕耠充骟忄龛 镟龀喉虺 狍潴忄腓 镱 嚯泐痂蜢圊 枢镫囗-体楹疣.

绣珞朦蜞蜩. 耱囹 镳邃耱噔脲沓 溧沓 3-鸪黜钽 耧铖蝈疱驽眄 玎 100 踱铕桁 觌稠橱眍 崇铍忄龛 耔礓痤祛 (什). 物桉囗 觌稠橱沓 蜞 爨沩瞅眍疱珙磬眈眍-蝾祛沭圄橱沓 (绦) 铖钺腓忸耱 铖眍忭桴 忄鸪囗虺 什.

妈珥圜屙 觌稠酬-礤轲钼崇筻氤玎龀轫 麒眄桕 痂玷牦 蝠囗耵铕爨龀 什 觌稠橱眍 漕耱钼仇龛 痤珩龛 耜脲痤 (誓醒). 需玷 蝠囗耵铕爨龀 什 誓醒 玑畴蠛螯 镳 腩赅氤玎龀 忸沩棂 溴斐弘稠崇圉晨 祛珙耱铎 虺氤, 磬忭铖虺 9 愠镥鸪眚屙耔忭桴 忸沩棂 2-疱骅斐, 镥痂 纛赅朦眍泐 磬狃牦 玎 溧龛扈 绦. 祟赅氤玎龀 忸沩棂 祛珙麝钼桴 耱痼牝箴圊 漕耱钼仇眍 玑畴蠛 痂玷 镥疱躅潴 什 醒.

孰钼 耠钼:觌稠橱眍 崇铍忄龛 耔礓痤, 觌稠橱眍 漕耱钼仇龛 痤珩龛 耜脲痤, 溴斐弘稠崇圉, 爨沩瞅眍-疱珙磬眈磬 蝾祛沭圄 . Myalovitska Analyzing Clinico-Neurological and Magnetic Resonance Imaging Indices in Patients with Clinically Isolated Syndrome and Evaluating the Risk of Its Conversion into Multiple Sclerosis Bogomolets National Medical University Introduction. The current neurological problem of predicting multiple sclerosis (MS) risk after the first clinical attack constitutes actual scientific and practical tasks. To refine on the methods of early diagnosis of multiple sclerosis, to study its clinical and neuroimaging features, to assess the risk of the conversion of clinically isolated syndrome into clinically definite multiple sclerosis (CDMS) are of great attention of both clinicians and patients.

Purpose. To assess the risk of the conversion of clinically isolated syndrome into clinically definite multiple sclerosis on the grounds of studying clinical magnetic resonance imaging manifestations of the first episode of demyelination for improve the diagnosis and disease prediction accuracy.

Materials and methods. 100 patients with clinically isolated syndrome have been examined. The studies were conducted by means of Siemens and Toshiba MRI systems 1.5 T. The number of hyperintense foci was assessed by means of T2WI MRI. The obtained data were used for evaluating the disease dynamics, def

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轻. 磬箨. 镳圉 耧斥痤岢. 吞老 踌屙 ..伢镨赅 23 (2)/2014 团滦嗡蚊策

inition of mono- or multifocal character of the lesion according to the clinical and magnetic resonance imaging characteristics with the view of detecting the risk of the conversion of CIS into CDMS.

Results. The obtained data were statistically processed by means of the software package Statistisa 8.0 ("StatSoft, Inc.", USA) and Microsoft Excel 2007 ("Microsoft Corporation", USA). To evaluate the correlation between the specific series we used Spearman rank correlation coefficient. The morbidity rate of multiple sclerosis in the examined patients was curved according to the Kaplan-Meier plots.

Key words: clinically isolated syndrome, clinically definite multiple sclerosis, demyelination, magnetic resonance imaging.

洛漕祛耱 钺 噔蝾疱:

腩忤鲫 烹屙 理囹铍忭 .戾.., 镳铘羼耦 赅翦漯 礤怵铍钽梃 吞 桁屙 ..令泐祛朦鲟. 冷疱襦: 疏邂, 狍朦忄 .劐怊屙觐, 13.

   

团尚蜗讶瘴宋貌淄 绽欣室判妊胰嗜

倚嚷纹臀岩 呐闲叛帛 侠植也

信绿酪委耐忍 佬倚纫翁

袜龀铐嚯 戾滂黜 嚓噤屐 锍耠滂镫铎眍 铖獬蜩 踌屙 ..伢镨赅 埋蝮. 绣忪囹羁漤栝 囵蝠栩 鲥 耔耱屐礤 囿蝾踌箜礤 玎踱铕囗 耧铍篦眍 蜿囗桧, 赍 箴噫嗪 礤 虺朦觇 耋汶钺斥, 嚯 忭篁鸪初 铕汔沓. 橡 龀 镟蝾腩愠 耧铖蝈鸪汔候 忮沐蜞蜩忭 滂耵箜牿 蜞 箴噫屙 礤疴钼羁 耔耱屐 忤汶涑 鸪珥钽 痤潴 屙鲥羿腩镟虺 蜞 镱氤礤轲铒囹抽.

体蜞. 妈怊屙 珈稠 礤轲铒耔躅腩愠黜桴 镱赅珥桕斥 玎脲骓铖虺 獬 蝠桠嚯铖虺 踵疣牝屦 镥疱岢泱 玎踱铕囗.

锑蝈鸪嚯 戾蝾滂. 袜扈 镳钼邃屙 钺耱彐屙 30 铖翅 祛腩漕泐 皴疱漤泐 獬牦,  踱铕畴 磬 欣 蜞 20 镳嚓蜩黜 玟铕钼桴 耧斥耱噔眍泐 獬牦.

彦疱漤抽 獬 耜豚溧 48,4 10,8 痤瓿. 相龀喉蜩 欣 狍腓 镱涑脲沓 磬 沭箫, 玎脲骓 獬 蝠桠嚯铖虺 玎踱铕囗 蜞 踵疣牝屦 镥疱岢泱 玎踱铕囗.

玉踌 镟龀喉蜞 镳钼钿桦铖 觌稠酬顤礤怵铍钽橱礤 钺耱彐屙, 礤轲铒耔躅腩愠黜 蝈耱筲囗.

绣珞朦蜞蜩. 泥沓 礤轲铒耔躅腩愠黜钽 蝈耱筲囗 怅噻嚯,  镟龀喉虺, 瓿 踱铕畴 磬 欣 岢朦 蝠桠嚯栝 鬣 爨腓 皴痤镱玷蜩忭栝 忄鸪囗 镥疱岢泱 耧铖蝈鸪汔腓顸 岢朦 忤疣驽沓 蝠桠铈沓 蜞 溴镳羼桠沓 痤珉噤.

项躅骅 疣犷螓:

奈梦挛 _ 徉黻钼耜钽 聍弪 桧滂忤潴嚯钽 镳邃镳桧桁囹咫 . 亦屙 "_" _201 泐溧 奏耱睇 嚓鲨铐屦睇 觐祆屦麇耜栝 徉黻 "Ravnaq-bank" (溧脲 "拎黻"), 腓鲥 青戾耱栩咫 橡邃皴溧蝈 橡噔脲龛 象豚蝾忄 .., 溴轳蜮簋泐 磬 铖眍忄龛 漕忮疱眄铖蜩 1 铗 02.01.201...

锣耔腓 锣耔朦邂梓 琉篑龛 孰噤徼眈觇 膻滂 彦痂 "物篑蝾眄 潴" 理眍蜞鲨 "帖 皴耱痤 髓漕 骅飧 磬 觌噤徼. 袜 龛骓屐 噫 疣珈妁屙 赈囵蜩瘥 觌噤徼眈觐泐 镳梓蜞. 卿羼 骅怏 潼觐 . 肉囗, 邈 驽磬 理磬 入龛黜 覃 烁, 祛 痤忮耥桕; 潼黝 暑痦咫栝 谚豚...

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